Clinical Trials
Clinical Research
Clinical research is medical research involving people. There are two different types of research:
-
Clinical trials are research studies performed on people focusing on a medical, surgical, or behavioral intervention. These help researchers determine if a new treatment, such as a new drug, diet, or medical device (eg. implants, etc.), is safe and effective in people. Often, a clinical trial is used to figure out if a new treatment is more effective and/or less harmful than the current standard of care.
-
Non-interventional research is very important to pave the way for future clinical trials. These studies involve gathering information and collecting physiological and biomarker data, which are all essential to help understand the disease mechanism and to develop new treatments.
Spinocerebellar Ataxia Studies
Single Patient 3-year Study for Troriluzole
Who is this study for?
SCA 3
How long will I need to participate?
3 Years
What is the treatment being studied?
Troriluzole or Placebo Tablet, taken by mouth
ENGAGE Ataxia
Who is this study for?
SCA diagnosis with medical clearance to exercise
What is the treatment being studied?
Physical Exercise
PRIME Ataxia
Who is this study for?
Ages 18-85; diagnosed with SCA
What is the treatment being studied?
Physical Exercise
Essential Tremor Studies
A Phase II, Double-Blind, Placebo-controlled, Dose-response Study of SAGE-324 for the Treatment of Essential Tremor
Who is this study for?
ET duration at least 3 years; main symptoms is BUE action tremor, moderate to severe ET
How long will I need to participate?
90 days
What is the treatment being studied?
SAGE-324 or Placebo Tablet, taken by mouth
Multiple System Atrophy Studies
A Multi-centered, Double-blind, Randomized, Placebo-controlled, Parallel Group Phase 2 Study of TEV-56286 for the Treatment of Patients with Multiple System Atrophy
Who is this study for?
30+ years old, diagnosed with MSA-C or MSA-P within the last 5 years, ability to ambulate 10 meters (can use a cane)
How long will I need to participate?
56 weeks
What is the treatment being studied?
Emrusolmin or placebo tablet, taken by mouth
A Phase III, Multi-center, Randomized Withdrawal and Long-Term Extension Study of Ampreloxetine for the Treatment of Symptomatic Neurogenic Orthostatic Hypotension in Participants with Multiple System Atrophy
Who is this study for?
Ages 30+; diagnosed with MSA-P or MSA-C, neurogenic Orthostatic Hypotension required with BP >/ 20 mmHg (systolic) or >/10 mmHg (diastolic) within 3 minute standing.
How long will I need to participate?
2.5 Years
What is the treatment being studied?
Ampreloxetine or Placebo Tablet, taken by mouth
Interventional, randomized, double-blind, placebo-controlled, optional open-label extension trial of Lu AF82422 in participants with Multiple System Atrophy
Who is this study for?
Ages 40-75, diagnosed with MSA-C or MSA-P, motor symptoms duration of less than 5 years
How long will I need to participate?
94 weeks with an optional open label extension of 72 more weeks
What is the treatment being studied?
Lu AF82422 or placebo, administered via IV infusion
Ataxia Studies
Caregiver of Ataxia Questionnaire
Who is this study for?
Ataxia diagnosis and caregiver
How long will I need to participate?
One time
What is the treatment being studied?
N/A, observational; one time questionnaire administered to both caregiver and patient
Iowa Gambling Task
Who is this study for?
Patients diagnosed with any Ataxia
What is the treatment being studied?
N/A; observational
Parkinson Disease Studies
A Phase II, Randomized, Double-blind, Placebo-controlled, Flexible-dosing, Parallel-group, Multicenter Study of the Efficacy and Safety of Suvecaltamide in the Treatment of Moderate to Severe Residual Tremor in Participants with Parkinson's Disease
Who is this study for?
Ages 40-80; PD with severe residual tremor; optimized on PD meds
How long will I need to participate?
23 Weeks
What is the treatment being studied?
Suvecaltamide or Placebo Tablet, taken by mouth
For more information or questions about clinical research and ongoing trials,
please call us at (212) 305-5779.